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C-RET PROTEIN
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DeCS
Descriptor
English
:
Proto-Oncogene Proteins c-ret
Descriptor
Spanish
:
Proteínas Proto-Oncogénicas c-ret
Descriptor
Portuguese
:
Proteínas Proto-Oncogênicas c-ret
Synonyms
English
:
Proto-Oncogene Protein Ret
Proto-Oncogene Protein c-ret
Receptor Tyrosine Kinase RET
Proto Oncogene Protein Ret
Proto Oncogene Protein c ret
Proto Oncogene Proteins c ret
Proto-Oncogene Proteins, ret
Ret, Proto-Oncogene Protein
c-ret, Proto-Oncogene Protein
c-ret, Proto-Oncogene Proteins
ret Proto Oncogene Proteins
c-ret Protein
ret Proto-Oncogene Proteins
Tree Number:
D08.811.913.696.620.682.725.400.087
D12.776.395.550.200.188.500
D12.776.543.131.500
D12.776.543.750.630.217
D12.776.624.664.700.194
Definition
English
:
Receptor protein-tyrosine kinases
involved in the signaling of GLIAL CELL-LINE DERIVED NEUROTROPHIC FACTOR
ligands
. They contain an extracellular cadherin domain and form a receptor complexes with GDNF RECEPTORS.
Mutations
in ret protein are responsible for
HIRSCHSPRUNG DISEASE
and
MULTIPLE ENDOCRINE NEOPLASIA
TYPE 2.
History Note
English
:
2006(1999)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50737
Unique Identifier:
D051096
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS